I have TMJ, shoulder and back pain and anxiety that I used to have to treat with a combination of NSAIDs like acetaminophen and meloxicam with beta blockers for the physical component of my anxiety. I sometimes have to use fairly high doses in order to make the pain and inflammation more bearable. TMJ especially can be extremely painful and can often make it difficult to speak or eat since both of my temporomandibular joints on my lower jaw will crack, pop out of place, and sometimes me entire jaw will be locked in one position for hours. I have used cannabis for about 6 years and whenever I do use it, I barely notice my pain and my TMJ usually doesn't bother me like it would normally. On the rare occasion that my jaw does begin to get inflammation, I don't have to take nearly as much acetaminophen to get rid of it (1 gram without cannabis down to 300-150 milligrams with it). My anxiety is bearable if it is by itself, but more times than not it will greatly exacerbate the TMJ because I will clench my jaw very hard without realizing it. Cannabis also calms me down quite a bit so I don't have to worry about my heart going too fast from nervousness or my TMJ getting worse. I prefer cannabis over my normal medications because cannabis won't damage my liver or GI tract like NSAIDs will.